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5490 (v.5) Oncology 628
Area: | School of Pharmacy |
Credits: | 25.0 |
Contact Hours: | 4.0 |
Lecture: | 1 x 4 Hours Weekly |
Co Requisite(s): | 5485 (v.5) Clinical Investigations 528
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6030 (v.6) Clinical Pharmacy 528
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6079 (v.6) Clinical Pharmacy 527
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Syllabus: | Review of malignant disease and its management. Clinical pharmacy services to the cancer patients. Basic concepts of cancer therapy, cell kinetics, pharmacokinetics of neoplastic drugs. Pharmacology, toxicology and therapeutic application of cytotoxic, hormonal and supportive care drugs used in the treatment of cancer. The clinical use of cytotoxic drugs, selection of complications, adverse reactions, interactions, toxicity, infections, administration methods and drug information. Combined modality treatment, interaction of radiotherapy and chemotherapy. Drug monitoring for patients affected by malignant disease. |
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Unit Outcomes: | On successful completion of this unit students will have - Developed an appreciation of the basic biology of cancer cell growth - in particular carcinogenesis, gene regulation, oncogenes, cell cycle growth characteristics, apoptosis, tumour mass growth kinetics, genetic instability, metatastic spread and cancer heterogeneity. Developed an appreciation the common complications of cancer in general - and have a practical knowledge for the management of pain, infection, hypercalcaemia and bone related complications and cachexia. Demonstrated an understanding of the relative importance and relationships between surgery, radiotherapy, cytotoxic therapy, hormonal therapy, immunotherapy and cytokine use for common cancers. Developed an understanding of the basic principles underlying the use of cytotoxic antineoplastic agents as they apply to - cyclical cytotoxic drug use, adjuvant and neoadjuvant therapies, rationale drug combination design, high-dose and dose intense therapies. Developed an appreciation forthe use of blood stem cell transplants in cancer treatment. |
Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases. |
Unit References: | Chabner B. and Longo D.L., (1996), Cancer Chemotherapy and Biotherapy - Principles and Practice, Philadelphia, Lippincott Co. De Vita V.R., Hellman S. and Rosenberg S.A., (Eds.), (1997) Cancer - Principles and Practice of Oncology, 5th ed., Philadelphia,Lippincott Co. Dorr R.T.and von Hoff D.D., (1994), Cancer Chemotherapy Handbook, 2nd ed., Norwalk, Appleton Lange. Peckham M., Pinedo H. and Veronesi U., (1995), Oxford Textbook of Oncology, Oxford, Oxford University Press. Gilman A.G., Goodman L.S., Rall T.W. and Morad F., (Eds.), (1985), Goodman and Gilman's -The Pharmaceutical Basis of Therapeutics, 7th ed., New York, MacMillan Publishing Company. Fauci A.S., Braunwald E., Isselbacher K., Wilson P.J.D., Martin J.B., Kasper D.L., Hauser S.L. and LongoD.L., (Eds.), (1998), Harrison's Principles of Internal Medicines, 14th ed., New York, McGraw-Hill International Book Company.Tannock I.F. and Hill R.P., (Eds.), (1992), The Basic Science of Oncology, 2nd ed., New York, McGraw-Hill. Pratt W.B., Ruddon R.W., Ensminger W.D.and Maybaum J., (1994), The Anti-Cancer Drugs, 2nd ed., New York, Oxford University Press. |
Unit Texts: | No prescribed texts. |
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Unit Assessment Breakdown: | Presentation with Summary/Case Reports 20%. Oral Examination 30%. Written Examination 50%. This is by grade/mark assessment. |
Field of Education: | 60100 Medical Studies (Narrow Grouping) | HECS Band (if applicable): | 3 |
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Extent to which this unit or thesis utilises online information: | Informational | Result Type: | Grade/Mark |
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Availability
| Year | Location | Period | Internal | Area External | Central External | | 2004 | Bentley Campus | Semester 2 | Y | | |
Area
External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |
Central
External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |
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