Area: | School of Biomedical Science |
Credits: | 25.0 |
Contact Hours: | 3.0 |
Lecture: | 1 x 3 Hours Weekly |
Other Requisite(s): | Admission: upon completion of Diploma of Technology, or equivalent at a Singapore Polytechnic
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Syllabus: | Tools of molecular genetics - enzymes, cloning vectors, labelling of DNA. Nucleic acid manipulation techniques - DNA, RNA extraction, hybridisation. Genomic and DNA library construction and screening. Polymerase chain reaction - principle methods, applications in clinical diagnosis. DNA sequencing and applications - Site-directed mutagenesis. Applications of DNA technology - genetic disease and cancer diagnosis. Gene therapy and genetic counselling. |
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Unit Outcomes: | On successful completion of this unit students will be able to - Demonstrate knowledge of basic molecular techniques used for nucleic acid based investigations. Appreciate and understand the safe use of radioactive substances in a laboratory environment.Perform a range of mathematical calculations related to the manipulation and interpretation of laboratory data. Demonstrate practical expertise with the performance of molecular techniques. Demonstrate competence in preparation of reagents for use in nucleic based applications. Demonstrate knowledge of the applications of the molecular techniques. |
Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases. |
Unit References: | Brown T.A., (1992), Genetics - A Molecular Approach, 2nd ed., Chapman and Hall. Mathews and Van Holde, (1990), Biochemistry, Benjamin Cummings Publishing Company. Lewin B., (1994), Genes V, Oxford University Press Inc. Wills C., (1992), Talking Genes, The Science Behind the Human Genome Project, Oxford University Press. |
Unit Texts: | Brown T.A., (1998), Gene Cloning - An Introduction, 3rd ed., Stanley Thomes Ltd. Old Primrose (Ed.), (1994), Principles of Gene Manipulation, 5th ed., Blackwell Scientific. |
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Unit Assessment Breakdown: | Mid Semester Examination 20%. Practical Tests and Assignments 50%. Final Examination 30%. This is by grade/mark assessment. |
Field of Education: | 10900 Biological Sciences (Narrow Grouping) | HECS Band (if applicable): | 2 |
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Extent to which this unit or thesis utilises online information: | Informational | Result Type: | Grade/Mark |
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Availability
| Year | Location | Period | Internal | Area External | Central External | | 2004 | BPI Intern'l Group S'pore | Trimester 1 | Y | | | | 2004 | BPI Intern'l Group S'pore | Trimester 2 | Y | | |
Area
External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |
Central
External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |
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