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12936 (v.2) Pharmaceutical Chemistry 200
Area: | School of Pharmacy |
Credits: | 50.0 |
Contact Hours: | 4.5 |
Lecture: | 1 x 2.25 Hours Weekly |
Tutorial: | 1 x 1 Hours Monthly |
Laboratory: | 16 x 3 Hours Yearly |
Prerequisite(s): | 7024 (v.5) Chemistry 122 or any previous version
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12935 (v.2) Pharmaceutics 100 or any previous version
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Syllabus: | Spectrophotometric analytical techniques. The concepts of pH, pKa and ionisation and their application in a pharmaceutical context. Reaction orders and reaction kinetics. Stereochemistry. Functional group chemistry, chemistry of carbohydrates, proteins, lipids, terpenes, steroids, vitamins, prostaglandins, thromboxanes and leukotrienes. Synthetic polymers. Drug - receptor interactions. Important pharmaceutical-chemical laboratory techniques. |
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Unit Outcomes: | On successful completion of this unit students will have developed familiarity with the roles of chemical functionality in drug structure, character and degradation. Demonstrated an understanding of the chemical characteristics of carbohydrates, proteins, lipids, terpenes, prostaglandins, thromboxanes and leukotrienes, steroidal drugs, vitamins as well as synthetic polymers. Demonstrated the ability to apply the concepts pf pH, pKa and ionisation, stereochemistry as well as reaction orders and reaction kinetics in a pharmaceutical context. Developed an awareness of the various mechanisms underlying drug-receptor interactions. Developed a familiarity with common pharmaceutical-chemical laboratory techniques. |
Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases. |
Unit References: | Beckett A.H. and Stenlake J.B., (1988), Practical Pharmaceutical Chemistry, Parts 1 and 2, 4th ed., London, Athlone Press. British Pharmacopoeia, (1998), London, HMSO. Ganellin C.R. and Roberts S.M., (Eds), (1993), Medicinal Chemistry - The Role of Organic Chemistry in Drug Research, 2nd ed., Academic Press. Hansch C., Sammes P.G. and Taylor J.B. (Eds.), (1990), Comprehensive Medicinal Chemistry, 6 Volumes, Pergamon Press. Morrison R.T. and Boyd R.N.,(1992), Organic Chemistry, 6th ed., Prentice Hall. Patrick G.L., (2001), An Introduction to Medicinal Chemistry, 2nd ed., Oxford University Press. Wermuth C.G.W., (Ed.), (1996), The Practice of Medicinal Chemistry, Academic Press. |
Unit Texts: | Pharmacuetical Chemistry 200 - Laboratory Course Book, Curtin University of Technology. Bailey P.S. and C.A., (2000), Organic Chemistry - A Brief Survey of Concepts and Applications, 6th ed., New Jersey, Prentice-Hall International Inc. Watson D.G.,(1999), Pharmaceutical Analysis - A Textbook for Pharmacy Students and Pharmaceutical Chemists, Churchill Livingstone. |
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Unit Assessment Breakdown: | Practical Laboratory Test 10%. Test (Semester One) 20%. Theory Laboratory Tests 20%. Final Examination 50%. This is by grade/mark assessment. |
Field of Education: | 60500 Pharmacy (Narrow Grouping) | HECS Band (if applicable): | 2 |
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Extent to which this unit or thesis utilises online information: | Informational | Result Type: | Grade/Mark |
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Availability
| Year | Location | Period | Internal | Area External | Central External | | 2004 | Bentley Campus | Full Year | Y | | |
Area
External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |
Central
External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |
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