314005 (v.1) Medicinal Chemistry and Drug Design 322
| Area: | Department of Chemistry |
|---|---|
| Credits: | 25.0 |
| Contact Hours: | 6.5 |
| Tuition Patterns: | The tuition pattern provides details of the types of classes and their duration. This is to be used as a guide only. Precise information is included in the unit outline. |
| Lecture: | 2 x 1 Hours Weekly |
| Tutorial: | 1 x 1 Hours Fortnightly |
| Laboratory: | 1 x 4 Hours Weekly |
| Prerequisite(s): |
313999 (v.1)
Medicinal Chemistry and Drug Design 222
AND 314003 (v.1) Biological Chemistry 321 OR 312495 (v.2) Biological Chemistry 321 or any previous version |
| Syllabus: | A molecular approach to drug design. Optimisation of lead compounds to drugs for clinical evaluation, including analysis of structure activity relationships and drug development strategies. Chemical principles and reactions vital to drug design and drug action will be emphasised using case studies of clinically important drugs. Selected topics in medicinal chemistry including anticancer, antihypertensives and opiate drugs. Brief introduction and overview of inorganic and organometallic chemistry in medicine. The use of metal complexes in diagnosis and therapy. Synthesis of organometallic complexes with ligands of biological relevance. Synthetic strategies for the preparation of organometallic and inorganic pharmaceuticals. Strategies for the covalent grafting of metal based labels to biological vectors. Photoelectric attenuation of x-rays for medical imaging. Laboratory experiments related to the chemistry topics in this unit. |
| Unit references, texts, outcomes and assessment details | The most up-to-date information about unit references, texts and outcomes, will be provided in the unit outline. |
| Field of Education: | 019907 Pharmacology |
| Result Type: | Grade/Mark |
Availability
Availability Information has not been provided by the respective School or Area. Prospective students should contact the School or Area listed above for further information.
