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3111 (v.3) Pharmaceutics 320
  
Area: | School of Pharmacy |  
Contact Hours: | 4.5 |  
Credits: | 50.0 |  
Lecture: | 1 x 2.5 Hours Weekly |  
Laboratory: | 1 x 2 Hours Weekly |  
Prerequisite(s): | 12936 (v.2) Pharmaceutical Chemistry 200  or any previous version 
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  | Drug stability - stability indicating assays. Chemical decomposition including hydrolysis, oxidation and photolysis. Effects of pH, solvent, dielectric constant and ionic strength on drug stability. Formulation of polypeptides. Sterilisation - dry heat, moist heat. Other forms of sterilisation. Sterilisation testing. Radiopharmacy. Dissolution and bioavailability. In-vivo determination of bioavailability using plasma and urinary data. Bioequivalence of drug products. Antimicrobial preservatives - incidence of microbial contamination, standards for the microbiological quality of pharmaceuticals. Choice of antimicrobial agent in formulated products. Drug delivery systems, drug targeting. |  
 
 Availability
| Year | Location | Period | Internal | Area External | Central External |  | 2004 | Bentley Campus | Full Year | Y |   |   |   
 
Area External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |  
Central External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |  
 
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