3111 (v.3) Pharmaceutics 320
| Area: | School of Pharmacy | 
| Contact Hours: | 4.5 | 
| Credits: | 50.0 | 
| Lecture: | 1 x 2.5 Hours Weekly | 
| Laboratory: | 1 x 2 Hours Weekly | 
| Prerequisite(s): | 12936 (v.2) Pharmaceutical Chemistry 200  or any previous version 
 | 
 
| Drug stability - stability indicating assays. Chemical decomposition including hydrolysis, oxidation and photolysis. Effects of pH, solvent, dielectric constant and ionic strength on drug stability. Formulation of polypeptides. Sterilisation - dry heat, moist heat. Other forms of sterilisation. Sterilisation testing. Radiopharmacy. Dissolution and bioavailability. In-vivo determination of bioavailability using plasma and urinary data. Bioequivalence of drug products. Antimicrobial preservatives - incidence of microbial contamination, standards for the microbiological quality of pharmaceuticals. Choice of antimicrobial agent in formulated products. Drug delivery systems, drug targeting. | 
| Year | Location | Period | Internal | Area External | Central External |  | 2003 | Bentley Campus | Full Year | Y |   |   |    | 
 
 
Current as of: October 30, 2003     13:11:55
 
 
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