|
| |
304890 (v.1) Pharmaceutical Formulation 527
Area: | School of Pharmacy |
Credits: | 12.5 |
Contact Hours: | 2.0 |
Lecture: | 1 x 1 Hours Weekly |
Workshop: | 1 x 1 Hours Weekly |
Syllabus: | General review of stability. Stability problems associated with intravenous fluids, total parenteral nutrition solutions including emulsion formulations and drug solutions stored in the frozen state. Stability calculations and conversion of basic data for use in practical situations. Influence of formulation on injection site, phlebitis and microbial contamination. Formulation of TPN solutions. Solubility problems associated with pharmaceutical systems such as intravenous fluids. Effect of change of solvent, common-ion effect, salting out, pH. Formulation of specific dosage forms. |
| |
Unit Outcomes: | On successful completion of this unit students will have - Developed an appreciation of the importance of formulation factors in providing efficient and effective dosage forms. Demonstrated an understanding of the stability and formulation problems involved with parerental preparations and with the formulation of polypeptides/proteins. Developed the ability to apply scientific data to solving applied problems. Developed the ability to use the literature material and write concise reports on specific aspects of formulation. |
Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases. |
Unit References: | Cartensen J.T., (2000), Drug Stability - Principles and Practices, New York, Marcel Dekker. Connors K.A., Amidon G.A. and Stella V.J., (1986), Chemical Stability of Pharmaceuticals, 2nd ed., New York, John Wiley and Sons. Florence A.T. and Attwood D., (1998), Physiochemical Principles of Pharmacy, 3rd ed., London, MacMillan Press. James K., (1986), Solubility and Related Properties, New York, Marcel Dekker. Trissel L.A., (Ed.), (2000), Handbook on Injectable Drugs, 11th ed., Bethesda, ASHP. Wells J.I., (1988), Pharmaceutical Preformulation, Chichester, Wiley. Wilson C.G.and Washington N., (1999), Physiological Pharmaceutics, 2nd ed., Chichester, Ellis Harwood. Yalkowskey S.H., (Ed.), (1981), Techniques of Solubilization of Drugs, New York, Marcel Dekker. |
Unit Texts: | No prescribed texts. |
| |
Unit Assessment Breakdown: | Assignments and Presentations 40%. Written Examination (2 hours duration, open book) 60%. This is by grade/mark assessment. In order to pass this unit, it is essential for the student to achieve at least 45% in the final examination and a satisfactory level in the other assessment areas. |
Field of Education: | 60500 Pharmacy (Narrow Grouping) | HECS Band (if applicable): | 2 |
|
Extent to which this unit or thesis utilises online information: | Informational | Result Type: | Grade/Mark |
|
Availability
| Year | Location | Period | Internal | Area External | Central External | | 2004 | Bentley Campus | Semester 1 | Y | | |
Area
External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |
Central
External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |
|
Click here for a printable version of this page
|
|
|
|
