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304233 (v.1) MT 532 - Genes and Evolution


 

Area:

School of Biomedical Science

Credits:

25.0

Contact Hours:

6.0

Individual Study:

1 x 6 Hours Weekly

Syllabus:

Genes in populations and evolution. Population genetics in Mendelian populations. Hardy Weinberg Rule - sex linkage, Wright's F statistics - random genetic drift. Linkage disequilibrium. Genetic processes in evolution. Selection fitness. Mutation, neutral theory. Introductory molecular aspects of evolution - Applications emphasising immunogenetics, hypervariable genetic markers, multigene families and DNA profiling.
 

Unit Outcomes:

On successful completion of this unit students will have - Developed a familiarity with the historical perspective and basic tenets of the Darwin-Wallace theory of evolution by natural selection. Developed an understanding of the molecular basis of polymorphism and mutation and an understanding if the relationship between allele and genotypic frequencies in randomly mating populations. Demonstrated an understanding of factors causing changes in gene frequency in populations. Developed the ability to contrast and compare the classical, balanced and neutral theories of selection. Demonstrated a comprehension of the evidence for selection and a familiarity with some applications of population and evolutionary genetics including human identification and its contemporary applications.

Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases.

Unit References:

Gillespie J.H., (1998), Population Genetics - A Concise Guide, Baltmore, John Hopkins University Press. Russell P.J., Genetics, 4th, 5th or 6th eds., Chapter 21. Dawkins R., (1995), River Out of Eden - A Darwinian View of Life, Basic Books.

Unit Texts:

Wetherall J.D., (2002), Genes in Populations and Molecular Evolution, Genetics 232 Manual. Hartl D.L., A Primer of Population Genetics, 3rd ed., Sunderland Mass, Sinaeur Associates Inc or Nelson Australia PL.
 

Unit Assessment Breakdown:

Assignments (2) 50%. Final Examination 50%. This is by grade/mark assessment.

Field of Education:

 60100 Medical Studies (Narrow Grouping)

HECS Band (if applicable):

3  

Extent to which this unit or thesis utilises online information:

 Informational  

Result Type:

 Grade/Mark


Availability

YearLocationPeriodInternalArea ExternalCentral External
2004Bentley CampusSemester 1Y  

Area
External
refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research.
Central
External
refers to external course/units run through the Curtin Bentley-based Distance Education Area

 
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