Area: | School of Biomedical Science |
Credits: | 25.0 |
Contact Hours: | 8.0 |
Lecture: | 1 x 3 Hours Weekly |
Individual Study: | 1 x 5 Hours Weekly |
Other Requisite(s): | Admission: dependent upon completion of Diploma of Technology, or equivalent at a Singapore Polytechnic.
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Syllabus: | Purification of molecules, elucidating the 3D structure of molecules, amino and nucleic acid, molecular forces, peptide bonds, protein secondary structrue, protein tertiary structure, graphic visualisation of molecules, protein and nucleic acid folding. |
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Unit Outcomes: | On successful completion of this unit students will have - A theoretical understanding of how to purify proteins to homogeneity. An awareness of the principle methodologies used in the 3D structural determination of macromolecules. An understanding of the principles of protein structure and their interactions and be able to describe the nature of molecular forces involved. An understanding of the key issues relating to the flexibility and folding of macromolecules and the prediction of their structure. Developed the skills to search, retrieve, and interpret data files (pdb) describing macromolecular structure from the data banks. Theoretical understanding of molecular forces involved in protein structure and in modelling protein structure and other macromolecules. Developed the practical skills, and knowledge, to use molecular visualisation programs to view and manipulate macromolecules to highlight their atomic detail and interactions. Demonstrated written communication skills through practical and written assignments or assessments. |
Texts and references listed below are for your information only and current as of September 30, 2003. Some units taught offshore are modified at selected locations. Please check with the unit coordinator for up-to-date information and approved offshore variations to unit information before finalising study and textbook purchases. |
Unit References: | Updated references supplied with unit outline as they change frequently. |
Unit Texts: | Branden, C. and Tooze, J., (1999) Introduction to Protein Structure, NY, Garland Publishing Inc. |
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Unit Assessment Breakdown: | Practical Assignment 50%. End of Semester Theory Examination 50%. This is by grade/mark assessment. |
Field of Education: | 60100 Medical Studies (Narrow Grouping) | HECS Band (if applicable): | 3 |
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Extent to which this unit or thesis utilises online information: | Not Categorised | Result Type: | Grade/Mark |
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Availability
| Year | Location | Period | Internal | Area External | Central External | | 2004 | BPI Intern'l Group S'pore | Trimester 1 | Y | | |
Area
External | refers to external course/units run by the School or Department, offered online or through Web CT, or offered by research. |
Central
External | refers to external course/units run through the Curtin Bentley-based Distance Education Area |
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