302417 (v.2) Biochemistry 202

Area:

School of Biomedical Science

Credits:

25.0

Contact Hours:

10.0

Individual Study:

1 x 10 Hours Weekly

Equivalent(s):

8804 (v.8) Biochemistry 231
301423 (v.4) BIO26 Biochemistry

Prerequisite(s):

    302409 (v.2) Chemistry For Life Sciences 101 or any previous version
    OR
    7230 (v.5) Chemistry 117 or any previous version
AND
302410 (v.2) How Cells Work 102 or any previous version

Syllabus:

Water and its biological importance. Proteins, protein architecture 1 and 2. The portrait of a soluble protein - haemoglobin. The portrait of an fibrous protein - collagen. Enzymes 1, 2 and 3. Bioenergetics 1 and 2. Concepts of metabolism. Glycolysis. Citric acid cycle. Energy from fatty acids. Electron transport chain 1 and 2. Fasting and fed state. Integration and regulation of metabolism. Pancreatic hormones. Insulin action and diabetes. Glucagon and cyclic AMP. Other hormonal mechanisms.

Unit Outcomes:

On successful completion of this unit students will have - Provided a more detailed exploration on how cells work by investigating the molecular components of cells and studying their properties and interactions. Developed an appreciation of the molecular logic of life. Gained a more detailed understanding of the structure and functions of principal biological macromolecules. Appreciated and understood protein structure and function. Understood how cells can extract the energy they need to survive through the breakdown of common biomolecules. Become familiar with the operation of molecular visualisation programs to explore protein structure. Understood the interrelationships between metabolic pathways. Developed critical thinking, independent research skills, data analysis, reasoning, and problem solving skills. Become familiar with the specialised language of biochemistry. Described in detail some of the common metabolic pathways. Described in detail some of the basic structures and functions of commonbiomolecules. Developed an understanding that science is a dynamic process - constantly changing and evolving. Provided a basic and sound, biochemical knowledge base for other studies in life sciences.

Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.

Unit References:

Berg J.M., Tymoczko, J.L., and Stryer, L. (2002). Biochemistry, 5th ed., NY, WH Freeman and Company. Devlin, T.M. (ed). (2002). Textbook of Biochemistry with Clinical Correlations, 5th ed., NY, Wiley-Liss. Garret, R.H. and Grisham C.M., (1999), Biochemistry, 2nd ed., NY, Saunders College Publishing. Nelson, D.L. and Cox, M.M. (2000), Lehninger Principles of Biochemistry, 3rd ed., Worth Publishers. Mathews, C.W., Van Holde, K.E., and Ahern, K.G. (2000) Biochemistry, 3rd ed., Benjamin/Cummings Publishing Company. Stryer, L. (1995). Biochemistry, 4th ed., NY, WH Freeman and Company. Voet, D., Voet, J.G. and Pratt, C.W. (1999). Fundamentals of Biochemistry, John Wiley and Sons. Wilson, K. and Walker, J. (eds). (2000). Principles and Techniques of Practical Biochemistry, 5th ed., Cambridge University Press. Zubay, G.L. (1999). Biochemistry, 4th ed., WC Brown Publishers.

Unit Texts:

Nelson, D.L. and Cox, M.M. (2000). Lehninger Principles of Biochemistry (3rd ed). Worth Publishers.

Unit Assessment Breakdown:

Assignments 50%, Examination 50%. This is by grade/mark assessment.

Year	Location	Period	Internal	Area External	Central External
2004	Bentley Campus	Special Term 1			Y
2004	Bentley Campus	Special Term 3			Y