2998 (v.4) Chemotherapy 224

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Area:	School of Pharmacy
Credits:	12.5
Contact Hours:	3.0
Lecture:	1 x 1 Hours Weekly
Laboratory:	1 x 2 Hours Weekly
Prerequisite(s):	11677 (v.3) Pharmaceutical Biology 233 or any previous version AND 11679 (v.3) Pharmaceutical Biology 231 or any previous version
Co Requisite(s):	8013 (v.5) Pharmacology 224 AND 12936 (v.2) Pharmaceutical Chemistry 200 AND 12937 (v.2) Pharmaceutics 200
Syllabus:	Selective toxicity - scope of antimicrobial chemotherapy. Classifications of antibiotics. Principles of treatment - clinical diagnosis, bacteriological diagnosis, reasons for treatment failure. The antimicrobial action, absorption, distribution, elimination, untoward effects and their place in chemotherapy of the following drug groups - sulphonamides and trimethoprim, betalactams, inhibitors of protein synthesis, macrolides and tetracyclines.
Unit Outcomes:	On successful completion of this unit students will have developed a scientific foundation in the understanding of the fundamentals underlying antibacterial chemotherapy. Developed the ability to describe the characteristics of the group of antimicrobials and the individual compounds studied. Developed the ability to compare individual compounds and select those most appropriate for standard scenarios.
Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.
Unit References:	Albert A., (1979), Selective Toxicity, 6th ed., London, Chapman and Hall. Australian Medicines Handbook - Current Edition. Therapeutic Guidelines, Antibiotic, Therapeutic Guidelines Limited, Current Edition, Melbourne. Kucers A. and Bennett N.M., (1996), The Use of Antibiotics - A Comprehensive Review With Clinical Emphasis, 5th ed., London, Butterworth-Heinemann Medical. O'Grady F., Lambert,H.P., Finch R.G. and Greenwood D., (1997), Antibiotic and Chemotherapy - Anti-infective Agents and Their Use inTherapy, 7th Ed, Churchill Livingstone. Ristuccia A.M. and Cunha B.A., (1984), Antimicrobial Therapy, New York, Raven Press.
Unit Texts:	Hardman J.G., Limbird L.E.and Lilman A.G., (2001), Goodman and Gilman's The Pharmacological Basis of Therapeutics, 10th Ed., New York, McGraw-Hill. Chemotherapy 224 - Practical Sessions. Curtin University of Technology.
Unit Assessment Breakdown:	Examination Paper (2 Hours) 70%. Mid-Semester Test 15%. Practical Assessment 15%. This is by grade/mark assessment.
Year Location Period Internal Area External Central External 2004 Bentley Campus Semester 2 Y