Syllabus: |
Metrology including mass and volume, qualitative and quantitative accuracy, triturates and aliquots. Percentage solutions, wt per mL, density and specific gravity. Alligation. The prescription, pharmaceutical latin. Scheduling of drug substances. Formulation, preparation, constituents and uses of aromatic waters, mouth washes and gargles, inhalations, linctuses, glycerols and other alcohols and syrups. Separation, methods of separation and clarification. Dosage form design - absorption of drugs, mechanisms and factors influencing absorption. General formulation of mixtures, solutions and suspensions, topical preparations applied tokeratinised surfaces (ointments, creams, lotions liniments), topical preparations applied to mucous surfaces (suppositories, enemas, pessaries, ophthalmic products), parenteral preparations (injections). Flavouring agents, colouring agents, including legislative control and toxicology. Posology - factors affecting drug dosage, infants and children's doses, introductory toxicology. Pharmaceutical solids, solids and the crystalline state-melting point, heat of fusion, sublimation, polymorphism, isomorphism. |