8363 (v.6) Biochemistry 232

Area:

School of Biomedical Science

Credits:

25.0

Contact Hours:

5.0

Lecture:

2 x 1 Hours Weekly

Tutorial:

1 x 0.5 Hours Weekly

Practical:

1 x 2.5 Hours Weekly

Prerequisite(s):

8804 (v.8) Biochemistry 231 or any previous version

Syllabus:

Overview, concepts and designs of metabolism. Including fat metabolism, ketone metabolism, pentose phosphate pathway, gluconeogenesis, nucleotide metabolism, and amino acid metabolism. Understand role and significance of membrane structure, membrane function, membrane composition and membrane transport. Know and understand the role of hormones and receptors in the control and integration of metabolism. In particular, the role of pancreatic hormones, adrenal hormones, calcium, and steroid hormones. Finally, the ability to solve problems, develop research skills and develop communication skills.

Unit Outcomes:

On successful completion of this unit students will have - Understood the language of biochemistry. Recognised and drawn simple biologically relevant molecules like sugars, fats, and amino acids. Appreciated the structure, function and organisation of many important biological molecules. Recognised significant functional and structural features of the macromolecules like proteins, carbohydrates and fats. Recognised significant functional and structural features of membranes. Understood the role of significance of hormones in their integration and control of metabolism. Demonstrated problems solving, research, and prepare communication skills. Demonstrated practical laboratory skills to explore skills to explore cell and tissue metabolism. Demonstrated competent laboratory skills to prepare common laboratory solutions. Understood the basic molecular organisation of a cell. Demonstrated an understanding of key metabolic pathways at the molecular level. Provided a balanced understanding of the physical, chemical and biological context in which each biomolecule, reaction or pathway operates.

Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.

Unit References:

Berg J.M., Tymoczko, J.L., and Stryer, L. (2002). Biochemistry, 5th ed., NY, WH Freeman and Company. Devlin, T.M. (Ed). (2002). Textbook of Biochemistry with Clinical Correlations, 5th ed., NY, Wiley-Liss. Garret, R.H. and Grisham C.M. (1999). Biochemistry, 2nd ed., NY, Saunders College Publishing. Nelson, D.L. and Cox, M.M. (2000) Lehninger Principles of Biochemistry, 3rd ed., Worth Publishers. Mathews, C.W., Van Holde, K.E., and Ahern, K.G. (2000). Biochemistry, 3rd ed., Benjamin/Cummings Publishing Company. Stryer, L. (1995). Biochemistry, 4th ed., NY, WH Freeman and Company. Voet, D. Voet, J.G. and Pratt, C.W. (1999). Fundamentals of Biochemistry. John Wiley and Sons. Wilson, K. and Walker, J. (Eds) (2000). Principles and Techniques of PracticalBiochemistry, 5th ed., Cambridge University Press. Zubay, G.L. (1999) Biochemistry, 4th ed., WC Brown Publishers.

Unit Texts:

Nelson, D.L. and Cox, M.M. (2000). Lehninger Principles of Biochemistry, 3rd ed., Worth Publishers.

Unit Assessment Breakdown:

Assignments 100%. This is by grade/mark assessment.

Year	Location	Period	Internal	Area External	Central External
2004	Bentley Campus	Semester 2	Y