8013 (v.5) Pharmacology 224

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Area:	School of Pharmacy
Credits:	25.0
Contact Hours:	6.0
Lecture:	1 x 4 Hours Weekly
Laboratory:	1 x 2 Hours Weekly
Prerequisite(s):	11677 (v.3) Pharmaceutical Biology 233 or any previous version AND 11679 (v.3) Pharmaceutical Biology 231 or any previous version
Co Requisite(s):	2998 (v.4) Chemotherapy 224
Syllabus:	Pharmacodynamics - Drugs acting at peripheral sites. Local hormones, inflammation and allergy. Antiplatelet and thrombolytic drugs. Immunosuppression. Drugs used to treat the epilepsies, neurodegenerative and behavioural disorders. Pharmacokinetics - Drug absorption, distribution, metabolism and elimination. Induction and inhibition of metabolism. Pharmacogenetics. Renal drug filtration, secretion and reabsorption. Bioavailability.
Unit Outcomes:	On successful completion of this unit students will have developed a knowledge of the mechanisms of drug absorption, distribution, metabolism and elimination. Demonstrated an appreciation of the relevance of this knowledge to Pharmacodynamics. Developed a clear and demonstrable understanding of pharmacodynamic principles. Developed the ability to apply these principles in describing the primary mechanisms of action of the classes of drugs included in the syllabus. Described and explained the mechanismsof common and less common but serious (life threatening) adverse effects and interactions for specific drugs and/or classes of drugs. Developed the ability to search appropriate scientific and medical literature sources in pharmacology and therapeutics and communicate findings in an appropriate form. Demonstrated an understanding of fundamental pharmacokinetic parameters and their application to drug dosage calculations based upon average serum steady state concentrations
Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.
Unit References:	Various journals and monographs on pharmacology, as advised.
Unit Texts:	Hardman J.G., Goodman Gilman A. and Limbird L.E., (2001) Goodman and Gilman's - The Phamacological Basis of Therapeutics, 10th ed., New York, Mc Graw-Hill. Page M.A., Pharmacokinetics Course Notes, Curtin University of Technology. Rowland M., Jozer, (1995), Clinical Pharmacokinetics, 3rd ed., Philadelphia, Lea and Febiger.
Unit Assessment Breakdown:	Assignment 10%. Multiple Choice Tests 15%. Practical/Tutorial Assessment 5%.Theory Written Paper 70%. This is by grade/mark assessment.
Year Location Period Internal Area External Central External 2004 Bentley Campus Semester 1 Y     2004 Bentley Campus Semester 2 Y