4713 (v.4) Medical Biotechnology 331

---

 

Area:	School of Biomedical Science
Credits:	25.0
Contact Hours:	8.0
Lecture:	1 x 2 Hours Weekly
Tutorial:	1 x 1 Hours Weekly
Practical:	1 x 5 Hours Weekly
Prerequisite(s):	8054 (v.8) Clinical Biochemistry 232 or any previous version AND 10076 (v.2) Molecular Biology 231 or any previous version
Syllabus:	Molecular biology of prokaryotes and eukaryotes. Molecular basis of disease. Recombinant DNA technology in medicine - cloning, sequencing and synthesis, gene probes as diagnostic reagents and DNA fingerprinting, polymerase chain reaction in clinical diagnostics, human pharmaceuticals - microbes, protein engineering, designer drugs, recombinant vaccines. Transgenics and gene therapy, social and legal aspects. Consists of five topics which examine techniques used in Biotechnology. The five topics are - enzymes, vectors and applications, southern blotting and applications, polymerase chain reaction and applications - genetic libraries, construction, use and identification of clones including sequencing and use of radioactive substances.
Unit Outcomes:	On successful completion of this unit students will have - Demonstrated knowledge of basic molecular techniques used for nucleic acid based investigations. Appreciated and understood the safe use of radioactive substances in a laboratory environment. Performed a range of mathematical calculations related to the manipulation and interpretation of laboratory data. Demonstrated practical expertise with the performance of basic molecular techniques. Demonstrated competence in preparation of reagents for use in nucleic based applications. Demonstrated knowledge of the applications of the molecular techniques.
Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.
Unit References:	Brown, T.A. (1998). Genetics - A Molecular Approach, 3rd ed., Chapman and Hall. Mathews and Van Holde. (1990). Biochemistry. Benjamin/Cummings Pub. Co. Lewin, V.B. (1994). Genes. Oxford, Oxford University Press Inc. Wills, C. (1992). Introns, Exons and Talking Genes - The Science Behind the Human Genome Project. Oxford, Oxford University Press.
Unit Texts:	Brown, T.A. (1998). Gene Cloning: An Introduction. (third edition). Stanley Thornes Ltd.
Unit Assessment Breakdown:	Mid Semester Test 30%. Practical tests (3) 30%. Final Theory Examination 40%. This is by grade/mark assessment.
Year Location Period Internal Area External Central External 2004 Bentley Campus Semester 1 Y