302503 (v.2) Integrative Physiology 206

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Area:	School of Biomedical Science
Credits:	25.0
Contact Hours:	10.0
Individual Study:	1 x 10 Hours Weekly
Anti Requisite(s):	8846 (v.7) Physiology 232 301421 (v.4) BIO28 Integrative Physiology
Prerequisite(s):	1644 (v.7) Human Biology 134 or any previous version AND 6934 (v.4) Human Biology 136 or any previous version AND 302415 (v.2) Structure and Function of the Body 107 or any previous version
Syllabus:	Blood, composition and function of plasma constituents. Anaemias, haemostasis, intrinsic and extrinsic pathways for blood clotting. Cardiovascular physiology, control of heart rate and stroke volume. Intrinsic and extrinsic regulation of blood flow/pressure. Heart failure, coronary heart disease, haemodynamics of blood flow. Capillary exchange, circulatory patterns. hypertension and blood pressure regulation. Respiratory physiology, respiratory mechanics, gas transport and release, obstructive and restrictive pulmonary disease. Alveolar ventilation and blood flow, oxygen and carbon dioxide transport, chemoreceptors and respiratory control, regulation of ventilation. Hypoxia and exercise. Renal physiology. Glomerator filtration, factors affecting GFR, glomerulonephritis, tubular reabsorption, plasma clearance, renal failure, countercurrent mechanisms, urea recycling, water and salt reabsorption. Body fluid and electrolyte balance - sodium, potassium, water and acid-base balance.
Unit Outcomes:	On successful completion of this unit students will have- Described the composition, physical characteristics and functions of blood. Described the composition of blood plasma and the functions of its constituents. Differentiated between haemostasis and the process of blood coagulation. Described the electrophysiology of the working heart. Identified the major factors that determine cardiac output. Compared and contrast the mechanisms by which blood pressure and blood flow are maintained at the systemic and tissue level. Compared and contrast the pathophysiology of left and right heart failure. Described anomalies of the cardiovascular system, in particular, cardiovascular responses to changes in blood pressure, haemorrhage, hypotension, exercise and heart failure. Investigated the interrelationship between the cardiovascular and respiratory systems and their role in the maintenance of body homeostasis. Detailed the mechanics of breathing with respect to the physical and chemical properties of the lung and alveolar tissue. Described how oxygen transport is influenced by changes in blood pH and temperature.
Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.
Unit References:	Berne, R.M. and Levy, M.N. (1993). Physiology. 3rd ed., Washington and St Louis, C.V. Mosby and Company. Ganong, W.F. (1991). Review of Medical Physiology.15th ed., New Jersey, Appleton and Lange. Guyton, A.C. (1991). Textbook of Medical Physiology. 8th ed., Philadelphia, WB Saunders and Company. Jennett, S. (1989). Human Physiology. Melbourne, Churchill Livingstone. Johnson, L.R. (1992). Essential Medical Physiology. New York, Raven Press. Patton, H.D. (1989). Textbook of Physiology. Vol 1and 2. Sydney, WB Saunders and Company. Rhoades, R. and Pflanzer, R. (1992). Human Physiology. 2nd ed., Philadelphia, Saunders College Publishing. Schmidt R.F. and Thews, G. (1989). Human Physiology. 2nd ed., Berlin, Springer-Verlag. Sperelakis, N. and Banks, R.O. (1993). Physiology. USA, Little, Brown and Company. Vander, A.J., Sherman, J.H., and Luciano, D.S. (1990). Human Physiology - The Mechanisms of Body Function. 5th ed., Sydney, McGraw-Hill. West, J.B. (1990). Respiratory Physiology - The Essentials. 4th ed., USA, Williams and Wilkins.
Unit Texts:	Silverthorn, D.U. (2001). Human Physiology - An Integrated Approach, 2nd ed., USA, Prentice Hall.
Unit Assessment Breakdown:	Theory Tests (3) 15%. Assignment (2,000 words) 10%. Practical Reports (4) 30%. Final Examination (3 hours) 45%. This is by grade/mark assessment.
Year Location Period Internal Area External Central External 2004 Bentley Campus Semester 2   Y   2004 Bentley Campus Special Term 1   Y   2004 Bentley Campus Special Term 3   Y