302410 (v.2) How Cells Work 102

Area:

School of Biomedical Science

Credits:

25.0

Contact Hours:

10.0

Individual Study:

1 x 10 Hours Weekly

Equivalent(s):

301428 (v.4) BIO18 How Cells Work or any previous version

Syllabus:

Life - a molecular process. The basic building block of life - the cell. The basic building blocks of the cell - water and molecular forces, carbohydrates, fatty acids and lipids, nucleotides and nucleic acids, amino acids and proteins. Introduction to enzymes. Concepts of energy and metabolism. Glycolysis and the citric acid cycle. The electron transport chain and oxidative phosphorylation. DNA replication, from DNA to protein. Chromosomes and gene regulation. Cell membrane structure - cell communication, cell division, cell cycle control and cell death.

Unit Outcomes:

On completion of this unit students will have - Provided an overview on 'how cells work' by investigating the molecular components of cells and studying their properties and interactions. Developed an appreciation of the molecular logic of life. Understood the structural and functional components of a cell. Gained an understanding of the structure and functions of principal biological macromolecules. Developed knowledge of how cells can extract the energy they need to survive through the breakdown of common biomolecules. Developed knowledge of the cell's molecular architecture and molecular components. Developed critical thinking, data analysis, reasoning, and problem solving skills. Become familiar with the specialised 'language' of cell biology, molecular biology, and biochemistry. Developed an understanding that science is a dynamic process - constantly changing and evolving. Described some of the common metabolic pathways and their interrelationships. Developed knowledge of information transfer in the cell and communication between cells. Prepared for more rigorous treatments in subsequent units of their degree course.

Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.

Unit References:

Alberts, B., Bray, D., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. (1998) Essential Cell Biology: An Introduction to the Molecular Biology of the Cell. Garland Publishing. New York. Becker, W.M. Keinsmith, L.J. Hardin, J. (2000) The Worldof the Cell. (fourth edition). San Francisco, Benjamin/Cummings. Bottomley, S. (1999). Lecture Notes for Biochemistry 231. Cooper, G.M. (1997). The Cell: A Molecular Approach. Oxford, Oxford University Press. Garret, R.H. and Grisham C.M. (1999). Biochemistry. (second edition). New York, Saunders College Publishing.NewPublishing. Goodsell, D.S. (1991). Inside a living cell. Trends in the Biochemical Sciences 16. pp203-206. Horton, H.R. Moran, L.A., Ochs, R.S., Rawn, J.D., and Scrimgeour, K.G. (1993). Principles of Biochemistry. Prentice Hall. Lehninger, A.L., Nelson, D.L. and Cox, M.M. (1993). Principles of Biochemistry. (second edition). Worth Publishers. Stoker, H.S. (1998). Organic and Biological Chemistry. Houghton Mifflin Company. Stryer, L. (1988).Biochemistry. (third edition). New York, WH. Freeman.

Unit Texts:

Alberts, B., Bray, D., Johnson, A., Lewis, J., Raff, M., Roberts, K. and Walter, P. (1998). Essential Cell Biology - An Introduction to the Molecular Biology of the Cell. NY, Garland Publishing.

Unit Assessment Breakdown:

Project 10%. Online Assessments (4) 40%. Examination 50%. This is by grade/mark assessment.

Year	Location	Period	Internal	Area External	Central External
2004	Bentley Campus	Semester 1		Y
2004	Bentley Campus	Semester 2		Y
2004	Bentley Campus	Special Term 1			Y
2004	Bentley Campus	Special Term 3			Y