301464 (v.2) MT 541 -Molecular Basis of Genetics

---

 

Area:	School of Biomedical Science
Credits:	25.0
Contact Hours:	3.0
Lecture:	1 x 1 Hours Weekly
Practical:	1 x 2 Hours Weekly
Syllabus:	Mendelian genetics from the molecular viewpoint and applications relevant to the diagnosis of inherited diseases. Cellular and molecular basis of inheritance - biological communication between generations and dominant versus recessive genes. Chromosomes, chromosomal abnormalities and disorders, single gene patterns of inheritance, polygenic patterns of inheritance, methods for the detection of genetic diversity and mutations and selected applications including tissue transplantation.
Unit Outcomes:	On successful completion of this unit students will have comprehension of the cellular and biochemical basis of Mendelian inheritance with an emphasis on the role of DNA as the genetic material. Developed an awareness of the general nature of the laboratory methods used for the diagnosis of inherited diseases, including chromosomal abnormalities. Developed an awareness of the nature and scope of the abnormalities responsible for the more common inherited diseases. Demonstrated a familiarity with some applications of genetic typing.
Text and references listed above are for your information only and current as of September 30, 2003. Please check with the unit coordinator for up-to-date information.
Unit References:	Brown T.A., (1998), Genetics - A Molecular Approach, 3rd ed., Chapman and Hall. Dawkins R., (1995), River Out of Eden - A Darwinian View of Life, Basic Books. Snustad D.P., Simmons M.J. and Jenkins J.B., (1997) Principles of Genetics, NY, John Wiley and Sons Inc. Additional reading from relevant journals.
Unit Texts:	Russell P.J., (1996/8), Genetics, 4th or 5th ed., Harper Collins Publishers.
Unit Assessment Breakdown:	Completion of Practicals 20%. Final Examination 50%. Project 30%. This is by grade/mark assessment.
Year Location Period Internal Area External Central External 2004 Bentley Campus Semester 1 Y