4152 (v.7) Pharmacokinetics 527
Area: School of Pharmacy Contact Hours: 4.0 Credits: 25.0 Lecture: 1 x 4 Hours Weekly
Pharmacokinetics. Model dependent/independent, and physiological approaches. Computers. Statistical moment theory and Bayesian analysis. Prediction of steady state drug plasma concentrations. Analytical techniques. Selectivity, sensitivity, and accuracy.Metabolites. First pass effect and gut metabolism. Factors modifying drug protein binding and metabolism. Drug dissolution testing - in-viro, in-vitro correlation. Assessment of Bioavailability. Applications to drug monitoring of plasma concentrations inedical conditions.
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