301271 (v.2) MT 614 - Leukemic Cytogenetics

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Area:	School of Biomedical Science
Contact Hours:	5.0
Credits:	25.0
Individual Study:	1 x 5 Hours Weekly
Prerequisite(s):	301107 (v.2) MT 610 - Cytogenetics or any previous version
Basic principles - bone marrow, blood specimens - when and why. Culturing - which cultures and why. Number of counts. Quality of spreads. Disease types and expected cytogenetic changes. Cytogenetic changes and alterations at the gene level, for example 9, 22 oncogenetics, tumour suppressors, present and absent. DMINs. Clone and clonal evolution.