11679 (v.3) Pharmaceutical Biology 231

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Area:	School of Pharmacy
Contact Hours:	5.0
Credits:	25.0
Lecture:	3 x 1 Hours Weekly
Laboratory:	1 x 2 Hours Weekly
Prerequisite(s):	6934 (v.4) Human Biology 136 or any previous version AND 12931 (v.2) Pharmaceutical Biology 120 or any previous version
Co Requisite(s):	11677 (v.3) Pharmaceutical Biology 233
Introduction to biocatalysis and bioenergetics, biological oxidation and reduction. Enzymes, enzyme kinetics and inhibition of enzyme action. Implications for drug metabolism. Basic biochemistry and metabolism of protein, fats and carbohydrates. Cholesterol, hypercholestrolaemia and serum lipoproteins. Biochemical control. Nucleotide metabolism. DNA and the gene. Cellular biochemistry of calcium and other ions. Biochemical principles in drug action. Insulin. digestion and absorption of carbohydrates, proteins and lipids. Nutrition - daily energy intake and expenditure. Energetic content of food types. Biochemistry of vitamins and trace elements and antioxidant vitamins.