3111 (v.3) Pharmaceutics 320
Area: | School of Pharmacy |
Contact Hours: | 4.5 |
Credits: | 50.0 |
Lecture: | 1 x 2.5 Hours Weekly |
Laboratory: | 1 x 2 Hours Weekly |
Prerequisite(s): | 12936 (v.2) Pharmaceutical Chemistry 200 or any previous version
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Drug stability - stability indicating assays. Chemical decomposition including hydrolysis, oxidation and photolysis. Effects of pH, solvent, dielectric constant and ionic strength on drug stability. Formulation of polypeptides. Sterilisation - dry heat, moist heat. Other forms of sterilisation. Sterilisation testing. An introduction to radioactivity - Its origins and general character, detection and measurement, units. Radiopharmacy. Dissolution and bioavailability. In-vivo determination of bioavailability using plasma and urinary data. Bioequivalence of drug products. Antimicrobial preservatives - incidence of microbial contamination, standards for the microbiological quality of pharmaceuticals. Choice of antimicrobial agent in formulated products. Evaluation of preservatives and special topics. |
Year | Location | Period | Internal | Area External | Central External | 2003 | Bentley Campus | Full Year | Y | | | |
Current as of: August 29, 2003 15:52:10
CRICOS provider code 00301J