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Curtin University
Courses Handbook 2011

This handbook contains information for courses and units at Curtin in 2011.
Information for current year courses and units is available at Courses Handbook 2010.

312495 (v.1) Medicinal and Biological Chemistry 321

Note

Tutition Patterns

The tuition pattern below provides details of the types of classes and their duration. This is to be used as a guide only. For more precise information please check your unit outline.

Unit references, texts and outcomes

To ensure that the most up-to-date information about unit references, texts and outcomes appears, they will be provided in your unit outline prior to commencement.

Area: Department of Chemistry
Credits: 25.0
Contact Hours: 6.5
Lecture: 2 x 1 Hours Weekly
Tutorial: 1 x 1 Hours Fortnightly
Laboratory: 1 x 4 Hours Weekly
Prerequisite(s): 312493 (v.2) Biological Chemistry 221 or any previous version
Syllabus: Medicinal chemistry Drug discovery, natural products (including indigenous organisms). Drug design, optimising target interactions and target access. Quantitative structure-activity relationships (QSAR). Selected topics in medicinal chemistry, topics may include: antibacterial, antiviral, anticancer, opiate drugs. Principles of molecular recognition, chemical sensor design including biosensors and detection techniques. Applications of sensors to clinical diagnostics and related measurements, examples may include: glucose detectors, metal ion sensors, oxygen sensors, alcohol detectors (breathalyzer). Introduction to the chemistry of heavy metals in aqueous biological environment. Enzymatic reactions and Michaelis-Menten kintetics. Metalloenzymes and their role into metabolism. Specific examples of metalloenzymes will be discussed and these may include: metalloenzymes with a structural functionality - Zn-finger proteins, metalloenzymes with a Lewis acid functionality - carboxypetidase, and metalloenzymes with a redox functionality - carbonic anhydrase. Iron based proteins: transport and storage of oxygen. Cellular respiration: electron transport chain. The use of metals in medicine. Carry out and report, in an appropriate manner, laboratory experiments related to the medicinal chemistry topics in the unit.
Field of Education: 010500 Chemical Sciences (Narrow Grouping)
SOLT (Online) Definitions*: Not Online
*Extent to which this unit or thesis utilises online information
Result Type: Grade/Mark

Availability

Year Location Period Internal Partially Online Internal Area External Central External Fully Online
2011 Bentley Campus Semester 1 Y        

Area External refers to external course/units run by the School or Department or offered by research.

Central External refers to external and online course/units run through the Curtin Bentley-based Distance Education Area

Partially Online Internal refers to some (a portion of) learning provided by interacting with or downloading pre-packaged material from the Internet but with regular and ongoing participation with a face-to-face component retained. Excludes partially online internal course/units run through the Curtin Bentley-based Distance Education Area which remain Central External

Fully Online refers to the main (larger portion of) mode of learning provided via Internet interaction (including the downloading of pre-packaged material on the Internet). Excludes online course/units run through the Curtin Bentley-based Distance Education Area which remain Central External