Courses Handbook 2009

311048 (v.1) Medicinal Chemistry 301


Area: School of Pharmacy
Credits: 12.5
Contact Hours: 3.5
** The tuition pattern below provides details of the types of classes and their duration. This is to be used as a guide only. For more precise information please check your unit outline. **
Lecture: 1 x 3 Hours Weekly
Tutorial: 1 x .5 Hours Weekly
Prerequisite(s): 311034 (v.1) Pharmaceutical Analysis 200
AND
311041 (v.1) Clinical Toxicology and Pharmacokinetics 222
Syllabus: Drug Discovery and Design: an overview of the stages, processes, technologies and approaches undertaken in modern drug discovery and design (emphasising the chemistry-based preclinical research performed by multinational pharmaceutical companies). The importance of drug screening and lead compound optimisation processes. Basic medicinal concepts and principles applied in drug discovery e.g. the drug pharmacophore, SAR studies, bioisosterism. The application of combinatorial chemistry and high throughput screening. the role of molecular modelling in drug design and structural biology (includes the use of x-ray crystallography in drug-receptor mapping). The concept of of prodrugs in drug design and delivery (includes a variety of examples from various drugclasses). Medicinal chemistry of selected drugs which include Peptide drugs, steroidal drugs, NSAIDS, Opiod analgesics, Antipsychotic and Anxyolytic agents, Cardiovascular drugs, Antibacterials, Antivirals, anticancer drugs, Antifungals, Antirparasitics,GIT system-acting drugs, Endocrine system-acting drugs.
** To ensure that the most up-to-date information about unit references, texts and outcomes appears, they will be provided in your unit outline prior to commencement. **
Field of Education: 019907 Pharmacology
SOLT (Online) Definitions*: Informational
*Extent to which this unit or thesis utilises online information
Result Type: Grade/Mark

Availability

Availability Information has not been provided by the respective School or Area. Prospective students should contact the School or Area listed above for further information.

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